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Summary of individual AUCinf (ng×hr/mL) values predicted by the PopPK model.
| Dose [mg/kg/day] | No. of Subjects | Mean (CV%) | Median [Min, Max] | |
|---|---|---|---|---|
| VBP15–002 | VBP15–004 | |||
| 0.25 | 9 | NA | 132 (30.5) | 120 [81, 230] |
| 0.75 | 6 | NA | 608 (43.2) | 589 [270, 1059] |
| 2 | 6 | 21 | 1130 (13.0) | 1150 [720, 1340] |
| 6 | 6 | 33 | 3361 (8.8) | 3340 [2320, 3990] |
NA: not applicable
