Figure 1.
The pathways linking endocrine disruptors to diabetes and its complications through mitochondrial dysfunction are discussed within this review. ROS, reactive oxygen species; TCA, tricarboxylic acid cycle; ADP, adenosine diphosphate; ATP, Adenosine triphosphate; H+, Hydrogen ion; Ca2+, calcium ions; Na+, sodium ion; I, complex I; II, complex II; III, complex III; IV, complex IV; Q, ubiquinone; Cytc, cytochrome c; FAD, flavin adenine dinucleotide; FADH2, flavin adenine dinucleotide; NADH, nicotinamide adenine dinucleotide; NAD+, nicotinamide adenine dinucleotide; O2, oxygen; H2O, Water.