Table 4.
Incidence rates, hazard ratios and confidence intervals of Gout in kidney donors and non-donors, stratified by All variables.
| Gout | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Non-KD | KD | |||||||||||
| Variable | N | PY | IR§ | N | PY | IR§ | cHR | (95% CI) | p-value | aHR$ | (95% CI) | p-value |
| Gender | ||||||||||||
| Female | 34 | 5980.28 | 5.69 | 27 | 4596.32 | 5.87 | 1.01 | (0.61, 1.68) | 0.963 | 1.75 | (0.92, 3.31) | 0.086 |
| Male | 78 | 5264.41 | 14.82 | 65 | 2932.55 | 22.17 | 1.48 | (1.07, 2.06)* | 0.019 | 1.75 | (1.23, 2.51)** | 0.002 |
| Age, years | ||||||||||||
| 20–34 | 28 | 3591.94 | 7.80 | 22 | 2322.27 | 9.47 | 1.20 | (0.69, 2.10) | 0.523 | 2.07 | (1.02, 4.18)* | 0.043 |
| 35–49 | 33 | 3187.76 | 10.35 | 26 | 3004.53 | 8.65 | 0.84 | (0.50, 1.41) | 0.512 | 1.20 | (0.67, 2.15) | 0.540 |
| ≥ 50 | 51 | 4464.98 | 11.42 | 44 | 2202.06 | 19.98 | 1.71 | (1.14, 2.56)** | 0.009 | 1.99 | (1.26, 3.13)** | 0.003 |
| Income, NTD/mo | ||||||||||||
| < 20,000 | 36 | 4138.13 | 8.70 | 25 | 1914.18 | 13.06 | 1.51 | (0.90, 2.51) | 0.116 | 1.90 | (1.09, 3.29)* | 0.023 |
| 20,000–38,999 | 51 | 4606.83 | 11.07 | 48 | 3793.31 | 12.65 | 1.13 | (0.76, 1.67) | 0.549 | 1.75 | (1.10, 2.76)* | 0.017 |
| ≥ 39,000 | 25 | 2499.73 | 10.00 | 19 | 1821.39 | 10.43 | 1.02 | (0.56, 1.85) | 0.947 | 1.83 | (0.87, 3.87) | 0.114 |
| Level of urbanization | ||||||||||||
| 1 (highest) | 24 | 1945.46 | 12.34 | 7 | 487.11 | 14.37 | 1.14 | (0.49, 2.66) | 0.757 | 1.43 | (0.54, 3.80) | 0.474 |
| 2 | 44 | 4727.83 | 9.31 | 39 | 3685.18 | 10.58 | 1.13 | (0.73, 1.74) | 0.576 | 1.62 | (1.01, 2.59)* | 0.044 |
| 3 (lowest) | 44 | 4571.40 | 9.63 | 46 | 3356.58 | 13.70 | 1.39 | (0.92, 2.10) | 0.118 | 2.09 | (1.30, 3.35)** | 0.002 |
| Comorbidities | ||||||||||||
| Hypertension | 49 | 3148.29 | 15.56 | 13 | 652.28 | 19.93 | 1.24 | (0.67, 2.28) | 0.496 | 1.06 | (0.53, 2.10) | 0.878 |
| Hyperlipidemia | 38 | 2862.45 | 13.28 | 11 | 725.05 | 15.17 | 1.10 | (0.56, 2.17) | 0.772 | 1.25 | (0.61, 2.56) | 0.549 |
| COPD | 35 | 2515.72 | 13.91 | 6 | 335.34 | 17.89 | 1.11 | (0.47, 2.65) | 0.813 | 1.03 | (0.41, 2.58) | 0.950 |
| Medication | ||||||||||||
| ACEI/ARB | 61 | 3732.62 | 16.34 | 28 | 1320.38 | 21.21 | 1.29 | (0.83, 2.02) | 0.260 | 1.30 | (0.79, 2.14) | 0.296 |
| Statins | 14 | 637.33 | 21.97 | 4 | 233.39 | 17.14 | 0.75 | (0.25, 2.28) | 0.611 | 1.23 | (0.36, 4.23) | 0.742 |
PY: person-years; IR: incidence rate; CI: confidence interval; HR: hazard ratio; §: Per 1000 person-year.
$: Adjusted HR estimated by the model including the variables of gender, age, monthly income, level of urbanization, comorbidities, and medications; *p < 0.05, **p < 0.01, ***p < 0.001.
n < 3: In order to avoid the issue of security and security, the government stipulates that if the data variable unit is less than 3 units or the value of less than 3 units can be calculated, the data cannot be carried.