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. 2024 Jul 26;44(35):e1700222024. doi: 10.1523/JNEUROSCI.1700-22.2024

Table 5.

Summary statistics for Figure 6b: pairwise comparisons for survival experiments

ALA dysfunction Comparison N (censor) Mean (days) Curve Comparison Χ2(df), p value Median survival (days) Median comparison p value

Number of comparisons: 8

Family-wise α: 0.05

Adjusted α: 0.006

rde-1(-) Uninfected 81 (14) 13.8 62.95(1), <0.001 14.0 <0.001
Infected 82 (18) 7.4 6.0
ceh-14(-); rde-1(-) Uninfected 27 (12) 10.6 30.59(1), <0.001 11.9 <0.001
Infected 84 (22) 3.6 2.5
rde-1(-) Uninfected 81 (14) 13.8 6.57(1), 0.01 14.0 0.82
Infected 27 (12) 10.6 11.9
ceh-14(-); rde-1(-) Uninfected 82 (18) 7.4 58.23(1), <0.001 6.0 <0.001
Infected 84 (22) 3.6 2.5

Bonferroni’s correction method was used to control for multiple comparison, alpha-level showed on the left. Test statistic and degrees of freedom are displayed for Mantel–Cox log-rank test for curve comparisons. Median value is shown as linear interpolation of 50th percentile of mortality curve, and comparison of these values was performed using Fisher's exact test. Statistical comparisons were performed using Oasis 2 (Han et al., 2016). Significant differences (below adjusted alpha) are displayed in bold.