Table 7.
Summary statistics for Figure 6d: pairwise comparisons for survival experiments
| flp-13 over-expression | Comparison | N (censor) | Mean (days) | Curve Comparison Χ2(df), p value | Median survival (days) | Median comparison p value | |
|---|---|---|---|---|---|---|---|
|
Number of comparisons: 12 Family-wise α: 0.05 Adjusted α: 0.004 |
Uninfected | rde-1(-) | 90 (18) | 12.0 | 3.45(1), 0.06 | 12.0 | 0.003 |
| ceh-17(-); rde-1(-) | 90 (18) | 11.1 | 10.1 | ||||
| Uninfected | rde-1(-) | 90 (18) | 12.0 | 5.57(1), 0.02 | 12.0 | 0.76 | |
| ceh-17(-); rde-1(-); HS:FLP-13 | 85 (24) | 13.5 | 12.1 | ||||
| Uninfected | ceh-17(-); rde-1(-) | 90 (18) | 11.1 | 12.45(1), <0.001 | 10.1 | 0.123 | |
| ceh-17(-); rde-1(-); HS:FLP-13 | 85 (24) | 13.5 | 12.1 | ||||
| Infected | rde-1(-) | 90 (27) | 6.7 | 33.91(1), <0.001 | 4.5 | <0.001 | |
| ceh-17(-); rde-1(-) | 82 (20) | 3.9 | 2.9 | ||||
| Infected | rde-1(-) | 90 (27) | 6.7 | 3.37(1), 0.07 | 4.5 | 0.88 | |
| ceh-17(-); rde-1(-); HS:FLP-13 | 79 (17) | 6.0 | 4.3 | ||||
| Infected | ceh-17(-); rde-1(-) | 82 (20) | 3.9 | 17.48(1), <0.001 | 2.9 | 0.002 | |
| ceh-17(-); rde-1(-); HS:FLP-13 | 79 (17) | 6.0 | 4.3 | ||||
Bonferroni’s correction method was used to control for multiple comparison, alpha-level showed on the left. Test statistic and degrees of freedom are displayed for Mantel–Cox log-rank test for curve comparisons. Median value is shown as linear interpolation of 50th percentile of mortality curve, and comparison of these values was performed using Fisher's exact test. Statistical comparisons were performed using Oasis 2 (Han et al., 2016). Significant differences (below adjusted alpha) are displayed in bold.