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Functionality of the antibody response. (A) Relative avidity index (RAI) of the anti-EGF antibody response at baseline and at 6 months. (B) Representative western blot evaluating the phosphorylation of the EGFR before and after vaccination. (C) Kinetics of the EGFR phosphorylation inhibition at baseline and at month 3 and 6. *** p < 0.001.
