Table 1.
Comparison of MCG sensor technologies and readiness for clinical adoption. Point-of-care infrastructure cost is defined as the monetary and practical cost to install and maintain infrastructure associated with a sensing technology. For example, cryogenics or magnetically shielded enclosures incur high capital costs to a hospital or clinic, as well as high logistical costs within a patient’s care pathway if they must transfer outside the emergency department for care. Practical demonstration of clinical utility refers to literature-supported demonstrations of disease classification at or exceeding sensitivity and specificity of the standard of care. The work presented in this publication opens the possibility for deployment of scalar OPMs (underlined last row) to perform such a demonstration of clinical utility.
| MCG Sensor Technology | Point-of-Care Infrastructure Cost (Primary Cost Driver) | Practical Demonstration of Clinical Utility |
|---|---|---|
| SQUIDs | High (inherent cost + cryogenics) | Yes [4,5,13] |
| SERF OPM | High (multi-layer magnetic shielding) | Yes [14,21,22] |
| Inductive coils | Low (system integration) | More Studies Needed 1 [23] |
| Fluxgate | Low (system integration) | No |
| TMR | Low (system integration) | No |
| Scalar OPM | Low (sensor) | No |
1 Clinical utility of QRS complex recorded via magnetic field time-derivative still under investigation.