Fig. 9. Signalling characteristics exhibited by the ZAC^L9′X mutants.

A. Representative traces of currents evoked by saturating Zn²⁺ concentrations in WT ZAC-, ZAC^L9′A-, ZAC^L9′V-, ZAC^L9′I- and ZAC^L9′T-expressing oocytes. 10 mM Zn²⁺ was used for WT ZAC and 1 mM Zn²⁺ was used for the ZAC^L9′X mutants, respectively. B. Representative traces of currents evoked by sustained application of saturating Zn²⁺ concentrations in WT ZAC- and ZAC^L9′I-expressing oocytes. 10 mM Zn²⁺ and 1 mM Zn²⁺ were used for WT ZAC and for ZAC^L9′I, respectively.