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. 2024 Aug 2;16(8):1030. doi: 10.3390/pharmaceutics16081030

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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In vitro release of ENG/EE from CLIP_HIGH IVR compared to CLIP_LOW IVR. (A) Cumulative (%) in vitro release of ENG/EE from CLIP_HIGH IVR compared to CLIP_LOW IVR. (B) Cumulative (µg) in vitro release of ENG/EE from CLIP_HIGH IVR compared to CLIP_LOW IVR. (C) Summary table of in vitro release profiles. (D) Summary table of in vitro release rates. All studies were carried out in triplicate in SVF pH 7 (sheep vaginal pH) release media. Each release curve represents the average ± standard deviation. Maximum standard deviation for in vitro cumulative release is less than 2%.