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. 2024 Jul 29;16(8):1217. doi: 10.3390/v16081217

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Evolution of HFMD cases over the epidemic period (2011–2012). (a) Monthly report of HFMD cases in North Vietnam. Number of HFMD cases reported to Vietnam Ministry of Health as routine surveillance in 2011 and 2012. (b) Weekly HFMD cases and severity distribution in Hải Phòng province. Each epidemiologic week begins on Monday. Mandatory reporting of the disease began in 2011. Mild cases are cases free of complication. Severe cases are characterized by febrile exanthemata’s symptoms affecting the central nervous system, frequently myoclonus and more severe neurological complications.