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. 2024 Aug 13;11(8):373. doi: 10.3390/vetsci11080373

Figure 3.

Figure 3

Efficacy of mRNA vaccines in guinea pigs. (A) Experiment design diagram for guinea pigs. (B) Normalized body weight of immunized guinea pigs (n = 3 per group). Red arrows indicate priming and boosting. (C) Detection of serum BVDV-1-specific neutralizing antibody titers on days 0, 28, 35, 42, 49, and 56 based on immunofluorescence inhibition (n = 3 for each group). (D) Effects of vaccinations on leukocytes (WBC), lymphocytes (LYM), intermediate cells (IMD), and granulocytes (GRA) on day 56 (n = 3 presented as black dots for each group). N.S., not significant, * p < 0.05.