Figure 2.

Showing modulation of host immune cell by P. aeruginosa and development of corneal ulcer. P. aeruginosa uses the pathogenic proteases and exo toxins in pathogenesis of corneal ulcer. After bacterial infection, lysosomal enzymes from activated polymorphonuclear neutrophils (PMNs) appears to be more critical in the case of P. aeruginosa keratitis than direct damage by P. aeruginosa exoenzymes. MMP9 directs the involvement of late-stage corneal ulcer tissue after P. aeruginosa infection of the cornea.