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Reduced epithelial identities in aged human AT1 cells. (A) Epithelial-Mesenchymal Transition (EMT)-related pathways identified by IPA analysis on aged AT1s. (B,C) Heatmap (B) and violin plots (C) showed the Epithelial Identity Score and expression of representative epithelial identity genes in AT1s of different age stages. Y, young (Age < 40), M, middle-aged (Age 40–60), O, aged (old) donors (Age > 60).
