Cytokine changes in response to CaboNivo or CaboNivoIpi at C2D1 and C3D1 relative to baseline. (A) VEGF. (B) PlGF. (C) IFNγ. (D) IL-6. (E) IL-8. (F) IL-10. (G) TNFα. n = 110 for C1D1, n = 96 for C2D1, and n = 91 for C3D1. Violin plots for cytokine level at baseline, separated between responders and nonresponders. Black bar represents median; upper red bar represents 75th percentile; lower red bar represents 25th percentile. IFN, interferon; IL, interleukin; PlGF, placental growth factor; TNF, tumor necrosis factor; VEGF, vascular endothelial growth factor.