Table 1.
Demographic and psoriasis disease characteristics in males and females.
| Characteristic | Biologic-naïve cohort (n = 3329) | Systemic therapy-naïve cohort (n = 1290) | ||||
|---|---|---|---|---|---|---|
| Males (n = 1726) | Females (n = 1603) | P-value a | Males (n = 682) | Females (n = 608) | P-value a | |
| Age, mean (SD), years | 49.5 (14.9) | 49.7 (15.6) | .623 | 46.7 (15.0) | 48.1 (15.4) | .096 |
| Race/ethnicity, n (%) | <.001 | <.001 | ||||
| White | 1401 (81.2) | 1360 (84.8) | 535 (78.4) | 501 (82.4) | ||
| Black | 56 (3.2) | 78 (4.9) | 22 (3.2) | 41 (6.7) | ||
| Asian | 75 (4.3) | 42 (2.6) | 28 (4.1) | 12 (2.0) | ||
| Hispanic or Latino | 144 (8.3) | 95 (5.9) | 80 (11.7) | 42 (6.9) | ||
| Other | 50 (2.9) | 28 (1.7) | 17 (2.5) | 12 (2.0) | ||
| Geographic region, n (%) | .003 | .128 | ||||
| North America | 1469 (85.1) | 1428 (89.1) | 612 (89.7) | 562 (92.4) | ||
| Europe | 226 (13.1) | 153 (9.5) | 55 (8.1) | 40 (6.6) | ||
| Latin America | 31 (1.8) | 22 (1.4) | 15 (2.2) | 6 (1.0) | ||
| Disease duration, years b | 11.51 | 11.61 | .836 | 7.58 | 7.87 | .678 |
| Baseline DLQI score (0-30) b | 9.16 | 9.82 | .008 | 10.91 | 11.45 | .173 |
| Baseline PGA score (0-5) b | 2.56 | 2.39 | <.001 | 2.65 | 2.51 | .018 |
| Historical peak PGA score (0-5) b | 2.95 | 2.87 | .084 | 2.88 | 2.69 | .007 |
| Baseline BSA, m2 b | 19.89 | 16.62 | <.001 | 20.01 | 15.97 | <.001 |
| Historical peak BSA, m2 b | 27.02 | 23.78 | .003 | 24.14 | 19.61 | .006 |
BSA, body surface area; DLQI, Dermatology Life Quality Index; PGA, Physician Global Assessment; SD, standard deviation.
aP-values for comparison of continuous variables between sexes were based on an independent sample t-test; P-values for categorical variables were obtained from exact Pearson chi-square tests.
bResults are reported as least-square mean values, adjusted for age, race, and body mass index.