Table 1. Demographic and clinical characteristics of the children with KD used in genetic analysis, stratified by size of CAA (n=1,270).
| Non-CAA (n=907) | Small CAA (<5 mm) (n=322) | Medium & giant CAA (≥5 mm) (n=41) | p | ||
|---|---|---|---|---|---|
| Age at onset (years) | 2.82±1.97 | 2.97±2.04 | 4.01±2.64 | 0.001 | |
| Sex | 0.017 | ||||
| Male | 518 (57.0) | 206 (64.0) | 30 (73.2) | ||
| Female | 389 (43.0) | 116 (36.0) | 11 (26.8) | ||
| Incomplete KD | 50 (5.5) | 98 (30.4) | 21 (51.2) | <0.001 | |
| Total fever days (days) | 6.22±1.92 | 6.55±2.54 | 9.93±5.10 | <0.001 | |
| 1st treatment | <0.001 | ||||
| Not treated | 0 (0.0) | 3 (0.9) | 2 (4.9) | ||
| IVIG, standard (2 g/kg) | 905 (99.8) | 312 (96.9) | 39 (95.1) | ||
| IVIG, non-standard (other than 2 g/kg) | 2 (0.2) | 4 (1.2) | 0 (0.0) | ||
| Aspirin only | 0 (0.0) | 2 (0.6) | 0 (0.0) | ||
| Others | 0 (0.0) | 1 (0.3) | 0 (0.0) | ||
| 1st IVIG non-responders | 225 (24.8) | 64 (20.3) | 14 (35.9) | 0.056 | |
Values are presented as number (%). Quantitative variables are shown as mean±standard deviation. Differences were assessed by analysis of variance test or χ2 test, with significant differences shown in bold.
CAA = coronary artery aneurysm; IVIG = intravenous immunoglobulin; KD = Kawasaki disease; Non-CAA = no coronary artery aneurysm.