Table 4. Additive effects of risk alleles for CAA formation in patients with Kawasaki disease.

Sex	Number of SNP used in analysis	Analysis group	Non-CAA	CAA group by aneurysm size*			p value
				Small	Medium	Giant
Male	6	Number of CAA risk alleles	1.88±1.361	1.90±1.371	3.86±2.012	4.25±1.282	3.39×10−13
		Number of weighted CAA risk alleles	5.19±4.711	5.40±4.851	12.60±9.572	15.3±8.022	1.98×10−15
Female	2	Number of CAA risk alleles	0.68±0.751	0.87±0.841,2	1.89±1.052,3	2.00±1.413	0.000002
		Number of weighted CAA risk alleles	3.03±3.331	3.88±3.741,2	8.43±4.702,3	8.94±6.493	0.000002

Data are presented as mean±standard deviation. Statistical analyses by analysis of variance and Tukey’s test. After Tukey’s test, values in the same column with different superscripts indicate significant differences between groups (p<0.05). Significant p values are shown in bold.

CAA = Kawasaki disease patients with coronary artery aneurysm (internal diameter ≥3 mm); Non-CAA = Kawasaki disease patients without coronary artery aneurysm; SNP = single nucleotide polymorphism.

^*Aneurysm size was classified as small (3–5 mm), medium (5–8 mm), or giant (≥8 mm).