Table 2.
Associations between PCA diagnosis and GILT impairment, with comparison to UKB either without (left) or with documented visual conditions (right). GILT impairment is defined using a standard cut-off (<5th percentile in UKB without visual conditions) using letter-based thresholds at 80% accuracy. Sensitivity, specificity, positive predictive and negative predictive values (PPV; NPV) are presented. Visual conditions in participants reaching the 80% accuracy cut-off are cataract (n=69), amblyopia (n=75), glaucoma (n=46) and low vision (n=4). UKB participants with stroke reaching 80% accuracy cut-off (n=16) have been excluded
| Letter-based threshold: 80% accuracy cut-off | ||||
|---|---|---|---|---|
| PCA diagnosis vs UKB (no visual dx) | PCA diagnosis vs UKB (visual dx) | |||
| Positive | Negative | Positive | Negative | |
| Positive | 15 | 62 | 15 | 9 |
| Negative | 3 | 1695 | 3 | 185 |
| Sensitivity | 83.3 | 83.3 | ||
| Specificity | 96.5 | 95.4 | ||
| PPV | 19.5 | 62.5 | ||
| NPV | 99.8 | 98.4 | ||