Table 5.
Statistics From the Analyses With Social Cognition and Functional Capacity as Mediators Between Neurocognition (CAI) and Functional Outcome
| X | Y | M | N | a/a’/a’’, estimates (CI) | b/b’/b’’, estimates (CI) | c, estimates (CI) | c’, estimates (CI) | Indirect effect estimate (CI) |
|---|---|---|---|---|---|---|---|---|
| Model 10 | ||||||||
| CAI Composite score | SLOF Int | FEIT | 483 | −1.93 (−2.47, −1.39) | .090 (0.014,0.165) | −1.49 (−1.9, −1.1) | −1.11 (−1.59, −0.62) | −0.17 (−0.34, −0.03) * |
| CAI Composite score | SLOF Int | TASIT1 | 483 | −1.49 (−1.79, −1.19) | 0.121 (−0.021,0.263) | † | ||
| CAI Composite score | SLOF Int | UPSA-B | 483 | −9.81(−11.17, −8.46) | 0.002 (−0.027,0.031) | † | ||
| Model 11 | ||||||||
| CAI Composite score | SLOF ELS | FEIT | 481 | −1.94 (−2.47, −1.39) | 0.037 (−0.05,0.12) | −3.46 (−3.97, −2.95) | −1.72 (−2.28, −1.17) | † |
| CAI Composite score | SLOF ELS | TASIT1 | 481 | −1.49 (−1.79, −1.19) | 0.20 (0.037,0.36) | −0.30 (−0.63, −0.02) * | ||
| CAI Composite score | SLOF ELS | UPSA-B | 481 | −9.81(−11.17, −8.46) | 0.14 (0.106,0.17) | −0.137 (−1.80, −0.097) * | ||
| Model 12 | ||||||||
| CAI Composite score | SLOF WS | FEIT | 482 | −1.93 (−2.47, −1.39) | 0.13 (0.06,0.19) | −2.34 (−2.70, −1.98) | −1.47 (−1.88, −1.06) | −0.25 (−0.42, −0.11) * |
| CAI Composite score | SLOF WS | TASIT1 | 482 | −1.49 (−1.79, −1.19) | 0.13 (0.01,0.25) | −0.19 (−0.39, −0.01) * | ||
| CAI Composite score | SLOF WS | UPSA-B | 482 | −9.81(−11.17, −8.46) | 0.04 (0.02, 07) | −0.42 (−0.69, −0.18) * | ||
Note: CAI, Cognitive Assessment Interview; SLOF, Specific Level of Functioning Scale; Int, interpersonal relationships; ELS, everyday life skills; WS, work skills; FEIT, Facial Emotion Identification Test; TASIT, The Awareness of Social Inference Test; UPSA-B, University of California San Diego (UCSD) Performance-based Skills Assessment.
In italics, P ≤ .05.
*Prerequisites to test for mediation are fulfilled, and the 95% CI of the indirect effect does not include zero and is therefore significant.
†Prerequisites to test for mediation are not fulfilled.
The results showed that (1) the direct effect of neurocognition on SLOF interpersonal relationships was reduced but remained significant, suggesting partial mediation through social emotion recognition (assessed with FEIT); (2) the direct effect of neurocognition on SLOF everyday life skills was reduced but remained significant, suggesting partial mediation through social emotion recognition (assessed with TASIT1) and functional capacity; (3) the direct effect of neurocognition on SLOF work skills was reduced but remained significant, suggesting partial mediation through social emotion recognition (assessed with both FEIT and TASIT1) and functional capacity.