Table 1.
Demographics of the study population, parasite density, test positivity (by qPCR) and RDT sensitivity by age group and sex
| Parameter | Category | N | qPCR Test positivity [95CI] (n/N) | p | Geometric Mean parasite density [95CI] | p | RDT sensitivity1 [95CI] (n/N) |
p |
|---|---|---|---|---|---|---|---|---|
| Age (years) | 0 to 5 | 35 (7.8%) | 48.6% [39.2, 58.0] (17/35) | 0.87 | 78.9 [4.0, 1556.8] | 0.02 |
70.6% [51.6, 89.5] (12/17) |
< 0.01 |
| 6 to 15 | 111 (24.7%) |
46.9% [37.4, 56.3] (52/111) |
41.3 [11.9, 143.3] |
73.1% [59.2, 86.9] (38/52) |
||||
| > 15 | 303 (67.5%) |
44.9% [37.7, 52.1] (136/303) |
6.3 [3.1, 12.8] |
44.9% [35.5, 54.2] (61/136) |
||||
| Sex | Male | 127 (28.3%) |
49.6% [39.8, 59.4] (63/127) |
0.58 | 12.4 [3.8, 40.1] | 0.87 | 47.6% [35.8, 59.5] (30/63) | 0.21 |
| Female | 322 (71.7%) |
44.1% [36.2, 52.0] (142/322) |
12.6 [6.0, 26.3] | 57.0% [46.6, 67.5] (81/142) | ||||
| Total | 449 (100%) |
45.7% [38.7, 52.6] (205/449) |
12.5 [6.7, 23.3] | 54.2% [44.3, 63.9] (111/205) |
1 For the RDT data, the results from all three RDTs were combined, with either RDT and either target (HRP2 or pLDH) positive counting as a positive test