Fig. 1.

Study population. The number of Dutch patients included in the INCIP study in the study period (n = 143), and the number of patients who had undergone an NIPT within the TRIDENT-2 study. In the TRIDENT-2 study 334499 NIPTs were performed between April 1 2017 and April 1 2021. aReviewed NIPT result according to the “Maastricht criteria”. Abbreviations: INCIP: International Network on Cancer, Infertility and Pregnancy. NIPT: non-invasive prenatal test. TRIDENT: Trials by Dutch Laboratories for Evaluation of Non-Invasive Prenatal Testing.