Table 1.
Malignancy suspicious-NIPTs per tumour types and tumour stages.
| Tumour type | Total number of pregnancy-associated cancers | Total suspicious-NIPTs according to “Maastricht criteria” (%) | Stage Ib: number of suspicious-NIPTs per number of patients | Stage IIb: number of suspicious-NIPTs per number of patients | Stage IIIb: number of suspicious-NIPTs per number of patients | Stage IVb: number of suspicious-NIPTs per number of patients | Unknown stage: number of suspicious NIPT per number of patients |
|---|---|---|---|---|---|---|---|
| Breast | 20 | 2 (10%) | 0 of 2 | 1 of 12 | 0 of 3 | 1 of 3 | 0 of 0 |
| Gynaecological | 19 | 2 (10%) | 0 of 11 | 0 of 4 | 2 of 4 | 0 of 0 | 0 of 0 |
| Haematological | 11 | 10 (90%) | 3 of 3 | 3 of 3 | 2 of 2 | 2 of 3 | 0 of 0 |
| Melanoma | 6 | 0 (0%) | 0 of 3 | 0 of 1 | 0 of 1 | 0 of 0 | 0 of 1 |
| Nasopharyngeal | 2 | 0 (0%) | 0 of 0 | 0 of 1 | 0 of 0 | 0 of 1 | 0 of 0 |
| Thyroid | 2 | 0 (0%) | 0 of 0 | 0 of 0 | 0 of 1 | 0 of 0 | 0 of 1 |
| Othera | 5 | 2 (40%) | 0 of 1 | 0 of 1 | 0 of 0 | 1 of 2 | 1 of 1 |
| Total non-haematological | 54 | 6 (11%) | 0 of 17 | 1 of 19 | 2 of 9 | 2 of 6 | 1 of 3 |
| Total haematological | 11 | 10 (91%) | 3 of 3 | 3 of 3 | 2 of 2 | 2 of 3 | 0 of 0 |
| Total | 65 | 16 (30%) | 3 of 20 | 4 of 22 | 4 of 11 | 4 of 9 | 1 of 3 |
Abbreviations: NA: not applicable.
a
Consists of four different cancer types, colon carcinoma (stage IV), thymoma (stage IV), bladder cancer (stage I), brain tumour (stage II) and carcinoma of unknown primary (NA).
b
The TNM-, FIGO- or WHO-classification was used for solid tumours, and the Ann Arbor staging system was used for the haematological cancers.