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. 2024 Aug 26;17:3163–3176. doi: 10.2147/DMSO.S460058

Table 2.

Methodological Characteristics of the Included Studies

Authors (Year) Country Age at Follow-Up Study Design Sample Size at Baseline Measure of CM Measures of MetS Type of CM Gender OR/HR (95% CI) Authors Conclusion
Danese et al (2009)66 New Zealand 32years Cohort 1037 Self-rated Childhood Maltreatment Questionnaire (CMQ) NCEP ATP III Cumulative abuse (physical abuse and sexual abuse) Male and female OR 1.39, 95% CIs (1.01–1.93) Significant association
Midei et al (2013)64 United States Mean-45.7yrs Cross-sectional 342 Self-rated Childhood Maltreatment Questionnaire (CMQ) NCEP ATP III Physical abuse Female only HR 2.02, 95% CIs (1.02–4.02) Significant association.
Emotional abuse Female only HR 1.37, 95% CIs (0.75–2.53) No significant association
Sexual abuse Female only HR 1.29, 95% CIs (0.63–2.62) No significant association
Lee et al (2014)63 United States 35–86yrs Cross-sectional 1234 Self-rated Childhood Maltreatment Questionnaire (CMQ) NCEP ATP III Physical abuse Men
Women
OR 2.40 95% CIs (1.29–4.44)
OR 1.47 95% CIs (0.90–2.41)
Significant association in men
No significant association
Emotional abuse Men
Women
2.24, 95% CIs (1.07 4.68)
1.30, 95% CIs (0.80–2.11)
Significantly associated with MetS in men only
No significant association
Sexual abuse Men
Women
0.84, 95% CIs (0.43–1.63)
OR 1.20, 95% CIs (0.79-0.182)
No significant association
No significant association
Cumulative abuse (physical and sexual, emotional/psychological abuse) Men OR 1.11 95% CIs (1.00–1.24) Significant association
Women OR 1.05 95% CIs (0.98–1.14) No significant association
Li et al (2019)65 United Kingdom 45yrs Cohort 18558 ACE Questionnaire and single questions NCEP ATP III Physical abuse Male and female OR1.14, 95% CIs (0.81–1.62) No significant association
Sexual abuse Male and female 1.37 (0.45–4.20) No significant association
Emotional abuse Male and female 1.16
(0.91–1.47)
No significant association
Neglect Male and female 1.08 95% CIs(0.89–1.32) No significant association
≥3 forms of CM (physical, sexual, emotional/ psychological abuse and neglect) Male and female 1.10 95% CIs (0.96–1.26) No significant association
Willemen et al (2022)67 Netherland 18–70yrs Cross-sectional 21,617 Short self-report questionnaire- derived from the NEMESIS Trauma questionnaire IDF ≥4 forms of CM (physical, sexual, emotional/ psychological abuse and neglect) Male and female 1.136 95% (0.78–1.63 No significant association

Abbreviations: NCEP-ATP111, National Cholesterol Education Program Adult; Treatment Panel III; IDF, International Diabetes Federation.