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Long-term follow up of patients with nmCRPC (NCT00849121). Patients were followed for 5 y for significant medical events. Shown are the times at which patients developed documented metastatic disease (■), started ARSI treatment (brown), or started docetaxel (blue). Time of death due to prostate cancer (●) or other cause (▲) is also shown. Subjects are ordered with respect to the pre-treatment PSA doubling time.
