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. 2024 Aug 29;16(1):2390176. doi: 10.1080/19490976.2024.2390176

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© 2024 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 5. — L. acidophilus inhibited BAs synthesis and enhanced BAs excretion. (a)-(b). Liver BAs classes and BAs profile of mice with severe and mild injury. n = 6 individuals/group. (c)-(d). Feces BAs classes and BAs profile of mice with severe and mild injury. n = 6 individuals/group. (e)-(f). Liver BAs classes and BAs profile of L. acidophilus treatment. n = 6/5/6, respectively. (g)-(h). Feces BAs classes and BAs profile of L. acidophilus treatment. n = 6/5/6, respectively. Data are expressed as the mean ± SEM. Two-tailed Student’s t-test or Mann–Whitney test. Columns with different letters differ significantly (P < 0.05). * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001. Abbreviations: BAs, bile acids.