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. 2024 Aug 30;15:7536. doi: 10.1038/s41467-024-51936-z

Fig. 5. Interdependency between ARGs and mobile genetic elements (MGEs) in viral genomes.

Fig. 5

Overall incidence of MGEs in genomes of (A) NCLDVs and (E) phages. Possibility of ARG-carriage in the MGE- and MGE+ genomes in (B) NCLDVs and (F) phages. Two-sided Chi-squared test is performed to test dependency between MGE-carriage and ARG-carriage in the viral genomes. Genomic potential of ARG-carriage in MGE- and MGE+ genomes in (C) NCLDVs and (G) phages. Two-sided Wilcoxon rank-sum test is performed to evaluate the statistical significance of the differences in genomic potential of ARG carriage between MGE+ and MGE- genomes. MGE + : genomes with at least one MGE. MGE-: genomes without any MGE. Data are presented as mean values ± SEM. Each data point is one genome. n = 56 (MGE-) and 1,360 (MGE + ) for NCLDVs. n = 14,910 (MGE-) and 25,367 (MGE + ) for phages. The y-axis was truncated to zoom in on values below 0.012% in (G). Histogram of ARG-MGE distance (kb) in (D) NCLDVs and (H) phages. Source data are provided as a Source Data file on Github107.