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. 2024 Aug 30;15:7553. doi: 10.1038/s41467-024-51781-0

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 3 — a In Vivo Imaging system (IVIS) localization of 50 μg Alexa750-labeled antibody (SpyC², B3, F4, F11, F3, F8, and C9) injected in 4T1 allografted mice with two mice per construct. Tumor area is encircled in red. b IVIS localization of C9 and F8 scFv² fused to albumin binding domain (ABD) in Karpas299 lymphoma xenografted mice after injection (0 h), 24 h, and 48 h after injection. c Ex vivo IVIS signals from the mice in panel b. 48 h after injection of ABD-control, ABD-C9, ABD-F8. d IVIS localization in patient-derived xenograft (PDX) model of neuroendocrine prostate cancer in male mice as described in b in vivo, and e ex vivo of mice from (d). 48 h, with radiant efficiency measured for each organ. f Ex vivo scanning in MiaPaca2 pancreatic xenograft model 24 h after injection of indicated proteins. Source data are provided as a Source data file.