Table 4.
Significantly Altered Functional Connectivities in PD Patients Compared with HCs
| Regions 1 | Category | Region 2 | Category | p-values | t-Values |
|---|---|---|---|---|---|
| ROL.R | Frontal | SOG.R | Occipital | 0.00009 | 4.32770 |
| OLF.L | Prefrontal | SOG.R | Occipital | 0.00089 | 3.56540 |
| ROL.R | Frontal | SPG.R | Parietal | 0.00001 | 5.14137 |
| SOG.R | Occipital | PUT.R | Subcortical | 0.00011 | 4.25433 |
| SPG.R | Parietal | PUT.R | Subcortical | 0.00001 | 4.93766 |
| REC.R | Prefrontal | DCG.L | Frontal | 0.00006 | −4.42763 |
| REC.R | Prefrontal | DCG.R | Frontal | 0.00001 | −4.89336 |
| ACG.L | Prefrontal | CAU.L | Subcortical | 0.00049 | −3.76694 |
| DCG.L | Frontal | CAU.L | Subcortical | 0.00055 | −3.72892 |
| ACG.L | Prefrontal | CAU.R | Subcortical | 0.00054 | −3.73545 |
| CAU.L | Subcortical | CAU.R | Subcortical | 0.00010 | −4.27647 |
Notes: NBS method identified a significantly altered network (11 nodes and 11 connections) in PD group relative to HCs. (P<0.01; threshold T=2.649).
Abbreviations: ROL.R, Rolandic operculum; OLF.L, Olfactory cortex; SOG.R, Superior occipital gyrus; SPG. R, Superior parietal gyrus; REC.R, Gyrus rectus; DCG.L, Median cingulate and paracingulate gyri; ACG.L, Anterior cingulate and paracingulate gyri; CAU. L, Caudate nucleus; PUT.R, Lenticular nucleus, putamen; DCG.R, Median cingulate and paracingulate gyri; CAU. R, Caudate nucleus.