Table 2.
Pulmonary function test at baseline, 24 weeks and difference between 0 and 24 weeks
| All (n = 94) | Discontinued group (n = 41) | Continued group (n = 53) | p-value | |
|---|---|---|---|---|
| FVC, % of predicted value, baseline | 69.2 ± 19.9 | 69.3 ± 17.3 | 69.2 ± (15.1) | 0.9893 |
| Category, n (%) | ||||
| < 70% | 46 (48.9) | 22 (53.7) | 25 (47.2) | 0.5327 |
| ≥ 70% | 48 (51.1) | 19 (46.3) | 28 (52.8) | |
| < 50% | 9 (9.6) | 5 (12.2) | 4 (7.5) | 0.4476 |
| ≥ 50% | 85 (90.4) | 36 (87.8) | 49 (92.5) | |
| < 50% | 9 (9.6) | 5 (12.2) | 4 (7.6) | 0.4725 |
| ≥ 50% and < 80% | 64 (68.1) | 29 (70.7) | 35 (66.0) | |
| ≥ 80% | 21 (22.3) | 7 (17.1) | 14 (26.4) | |
| FVC, % of predicted value, at 24 weeks | 66.7 ± 16.3 | 65.4 ± 14.9 | 67.5 ± 17.0 | 0.6539 |
| Change FVC between 0 and 24 weeks | − 1.7 ± 8.6 | − 1.3 ± 1.5 | − 0.1 ± 1.0 | 0.5076 |
| FEV1,% of predicted value, at baseline | 76.1 ± 17.1 | 78.3 ± 18.0 | 74.5 ± 16.3 | 0.2900 |
| FEV1,% of predicted value, at 24 weeks | 73.4 ± 17.8 | 74.5 ± 16.7 | 73.0 ± 18.4 | 0.7824 |
| DLco, % of predicted value, at baseline | 48.0 ± 15.5 | 51.3 ± 14.4 | 46.0 ± 15.9 | 0.1711 |
| DLco, % of predicted value, at 24 weeks | 44.3 ± 15.9 | 42.0 ± 32.1 | 45.1 ± 39.0 | 0.5866 |
| Change DLco between 0 and 24 weeks | − 0.7 ± 9.2 | − 4.0 ± 6.4 | 0.47 ± 9.8 | 0.1724 |
Values are displayed as number (%), mean ± standard deviation
DLco diffusion capacity of carbon monoxide, FEV1 forced expiratory volume in one second, FVC forced vital capacity