Guerra 2008.
Methods | Randomised, controlled, single‐centre study conducted in Brazil Grading of quality: Randomisation = C Blinding = C Intention‐to‐treat analysis = B Follow‐up = D Overall quality grading = C |
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Participants | 120 children aged 14 years or less undergoing adenotonsillectomy. Study and control groups were well matched in terms of age and sex. | |
Interventions | Postoperative amoxicillin 50 mg/kg/day for 7 days | |
Outcomes | Primary outcomes: pain, analgesic consumption and secondary haemorrhage Secondary outcomes: fever and time taken to resume normal diet and activities Period of observation: 7 days |
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Notes | Exclusion criteria: allergy to amoxicillin or haematological disorder. Surgical technique was controlled: all patients underwent dissection, with no use of electrocautery, anaesthetic technique not mentioned as controlled. Follow‐up: 95 (%) patients (43 in the antibiotic group and 52 in the control group) completed follow‐up |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Unclear risk | B ‐ Unclear |