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. 2012 Dec 12;2012(12):CD005607. doi: 10.1002/14651858.CD005607.pub4

Guerra 2008.

Methods Randomised, controlled, single‐centre study conducted in Brazil
Grading of quality: 
 Randomisation = C 
 Blinding = C 
 Intention‐to‐treat analysis = B 
 Follow‐up = D
Overall quality grading = C
Participants 120 children aged 14 years or less undergoing adenotonsillectomy. Study and control groups were well matched in terms of age and sex.
Interventions Postoperative amoxicillin 50 mg/kg/day for 7 days
Outcomes Primary outcomes: pain, analgesic consumption and secondary haemorrhage
Secondary outcomes: fever and time taken to resume normal diet and activities
Period of observation: 7 days
Notes Exclusion criteria: allergy to amoxicillin or haematological disorder. Surgical technique was controlled: all patients underwent dissection, with no use of electrocautery, anaesthetic technique not mentioned as controlled.
Follow‐up: 95 (%) patients (43 in the antibiotic group and 52 in the control group) completed follow‐up
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear