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. 2024 Aug 31;12:93. doi: 10.1186/s40364-024-00644-3

Table 7.

Clinical trials of mRNA vaccines encoding Ab

Cancer type NCT number Drug administration  Phase Status  Delivery system Result
Solid Tumor NCT05262530 BNT142 (mRNA encoding antibodies targetingCD3 × CLDN6) Recruiting  LNP Ongoing
Reproductive system tumors (mainly ovarian cancer) ovarian cancer NCT04683939 BNT141 (mRNA encodinganti-Claudin18.2 monoclonal antibody) I/II Recruiting  LNP Ongoing