Table 1.

Effect of NG on hepatic function-related biochemical parameters in the serum of ICR mice with GEF-induced liver injury (mean ± SD), n = 10

Group	ALT (U/L)	AST（U/L）	LDH (U/L)	ALP (U/L)
Control	27.77±3.01	67.67±11.56	5.39±0.435	129.5±21.01
GEF	175.60±12.72**	341.0±25.73**	16.26±0.871**	476.0±24.35**
NG 50+GEF	122.90±14.53#	226.5±21.46##	11.44±1.032#	372.9±30.06##
NG 100+GEF	83.07±8.02##	135.7±17.07##	7.72±0.447##	301.6±29.98##
NG 200+GEF	51.85±3.36##	61.71±14.07##	6.43±0.72##	241.6±29.06##

Compared with control group,*P<0.05,**P<0.01, Compared with GEF group, #P<0.05, ##P<0.01

GEF: Gefitinib; NG: Naringin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; LDH: Lactate dehydrogenase; ALP: Alkaline phosphatase