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. 2024;27(10):1309–1316. doi: 10.22038/ijbms.2024.76852.16623

Table 3.

Histopathological evaluation of liver tissue of ICR mice with GEF-induced liver injury

Parameters Control GEF NG50 + GEF NG100 + GEF NG200 + GEF
Hydropic degeneration in hepatocytes + +++ ++ +
Focal necrosis +++ + ++ +
Neutrophils infiltration +++ + ++ +

(−) No variation, (+) Small variation, (++) Medium variation, (+++) Big variation

GEF: Gefitinib; NG: Naringin