Table 1.

Study sample characteristic stratified by annual progression rate of aortic stenosis.

Variables		Total	Slow or no AS progression	Fast AS progression	p value
		(n = 170)	n = 135 (79.4%)	n = 35 (20.6%)
Age, yr		66.84 $\pm$ 12.64	65.64 $\pm$ 11.52	71.46 $\pm$ 15.61	0.005
Male, n (%)		61 (35.9)	43 (31.8)	18 (51.4)	0.031
BMI, kg/$m^2$		26.99 $\pm$ 6.43	28.04 $\pm$ 6.60	22.94 $\pm$ 3.48	0.001
Alcohol intake, n (%)					0.466
	Never	137 (80.6)	111 (82.2)	26 (74.3)
	Ever	32 (18.8)	24 (17.8)	8 (22.8)
Smoking, n (%)					0.098
	Never smoked	138 (81.2)	113 (83.7)	25 (71.4)
	Ever smoked	32 (18.8)	22 (16.3)	10 (28.6)
SBP, mmHg		132.80 $\pm$ 21.10	132.98 $\pm$ 21.02	132.11 $\pm$ 21.70	0.618
DBP, mmHg		75.22 $\pm$ 12.88	73.71 $\pm$ 13.05	75.61 $\pm$ 12.86	0.579
PP, mmHg		57.58 $\pm$ 16.91	57.36 $\pm$ 15.62	58.40 $\pm$ 21.42	0.870
GLU, mmol/L		6.01 $\pm$ 1.93	6.13 $\pm$ 1.98	5.54 $\pm$ 1.64	0.063
TC, mmol/L		4.75 $\pm$ 1.31	4.82 $\pm$ 1.12	4.74 $\pm$ 1.36	0.737
TG, mmol/L		1.29 $\pm$ 0.87	1.26 $\pm$ 0.84	1.43 $\pm$ 0.95	0.278
HDL-C, mmol/L		1.25 $\pm$ 0.39	1.27 $\pm$ 0.40	1.18 $\pm$ 0.31	0.195
LDL-C, mmol/L		3.00 $\pm$ 0.99	2.97 $\pm$ 1.05	3.10 $\pm$ 0.76	0.231
Cr, µmol/L		103.13 $\pm$ 108.66	104.51 $\pm$ 120.28	97.78 $\pm$ 40.32	0.027
UA, µmol/L		431.19 $\pm$ 141.77	434.36 $\pm$ 143.45	418.96 $\pm$ 136.38	0.482
HTN, n (%)		111 (65.3)	92 (68.1)	19 (54.3)	0.163
T2DM, n (%)		44 (25.9)	30 (22.2)	14 (40.0)	0.030
CHD, n (%)		43 (25.3)	27 (20.0)	16 (45.7)	0.002
Aortic stenosis, n (%)					0.780
	Mild	77 (45.3)	62 (45.9)	15 (42.9)
	Moderate	70 (41.2)	56 (41.5)	14 (40.0)
	Severe	23 (13.5)	17 (12.6)	6 (17.1)
ΔVmax, m/s		0.38 $\pm$ 0.87	0.14 $\pm$ 0.43	1.34 $\pm$ 1.36	0.001
Vmax, m/s		0.38 $\pm$ 0.87	3.20 $\pm$ 0.77	3.34 $\pm$ 0.91	0.356
PG, mmHg		33.47 $\pm$ 21.00	33.30 $\pm$ 20.97	34.11 $\pm$ 21.44	0.348
EF, %		63.55 $\pm$ 10.56	64.03 $\pm$ 10.14	61.71 $\pm$ 12.04	0.249
Follow-up, months, median (interquartile range)		30.7 (17.9, 41.3)	34.9 (19.3, 43.0)	24.0 (10.1, 31.9)	0.01

Data are median (interquartile range), mean $\pm$ SD, or percentage (unless otherwise indicated). According to AS annual progression rate, characteristics are from the study population (n = 170). BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; PP, pulse pressure; GLU, glucose; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; AS, aortic stenosis; Cr, serum creatinine; UA, uric acid; HTN, hypertension; T2DM, type 2 diabetes mellitus; CHD, coronary heart diseases; $\mathrm{\Delta }$Vmax, m/s/year, annual change in peak aortic velocity; PG, pressure gradient; EF, ejection fraction.