Table 3.
Adjusted OR for fast progression rate of aortic stenosis associated LDL-C joint T2DM.
Exposure T2DM | LDL-C, mmol/L | Total (n) | Unadjusted | Partially adjusted model | Fully adjusted model | |||
n = 170 | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | ||
n (%) | ||||||||
No | 2.15 | 30 (17.6) | Ref = 1 | |||||
2.15–3.14 | 41 (24.1) | 4.70 (0.91–8.36) | 0.208 | 1.20 (0.96–6.55) | 0.088 | 1.30 (0.99–7.78) | 0.167 | |
3.14 | 55 (32.4) | 2.79 (0.52–5.05) | 0.089 | 1.56 (1.21–2.02) | 0.017 | 1.60 (1.17–3.29) | 0.040 | |
Yes | 2.15 | 13 (7.6) | 2.46 (0.30–3.68) | 0.379 | 2.10 (1.57–2.79) | 0.251 | 2.21 (0.49–4.32) | 0.527 |
2.15–3.14 | 15 (8.8) | 3.64 (1.53–4.63) | 0.013 | 2.21 (1.96–5.57) | 0.006 | 2.67 (1.65–7.10) | 0.004 | |
3.14 | 16 (9.4) | 1.75 (1.04–8.74) | 0.018 | 2.59 (1.17–6.40) | 0.005 | 3.20 (1.07–5.34) | 0.022 | |
p for interaction | 0.021 |
Unadjusted model; Model 1-partially adjusted for age and gender; Fully adjusted model adjusted for model-1 plus BMI, TC, Cr, HTN and CHD. OR, odds ratio; CI, confidence interval; LDL-C, low-density lipoprotein cholesterol; T2DM, type 2 diabetes mellitus; BMI, body mass index; TC, total cholesterol; Cr, creatine; HTN, hypertension; CHD, coronary heart disease.