Table 2.
Baseline characteristics of study participants and assessment by BMI (n = 7620).
Characteristics | Control group (n = 5044) | Overweight/Obese group (n = 2576) | t/χ2 value | p value | |
Demographics | |||||
Sex, Men, n (%) | 2310 (62.1) | 1410 (37.9) | 54.532 | 0.001 | |
Age (years) | 58.97 13.12 | 57.48 12.83 | 4.724 | 0.001 | |
Hypertension, n (%) | 2659 (52.7) | 1751 (68) | 162.817 | 0.001 | |
Diabetes, n (%) | 1065 (21.1) | 758 (29.4) | 64.717 | 0.001 | |
Current smoker, n (%) | 429 (8.5) | 240 (9.3) | 1.403 | 0.236 | |
Everyday drinking, n (%) | 313 (6.2) | 167 (6.5) | 0.223 | 0.637 | |
Medications | |||||
Antihypertension, n (%) | 780 (15.5) | 682 (26.5) | 133.340 | 0.001 | |
Anti-diabetes, n (%) | 416 (8.2) | 315 (12.2) | 31.157 | 0.001 | |
Anthropometrics | |||||
Height (cm) | 164.26 7.66 | 165.1 8.28 | –4.442 | 0.001 | |
Body mass (kg) | 59.94 7.98 | 75.83 11.04 | –71.878 | 0.001 | |
BMI (kg/m2) | 22.15 1.94 | 27.73 2.8 | –101.710 | 0.001 | |
SBP (mmHg) | 136.41 26.86 | 141.88 25.32 | –8.579 | 0.001 | |
DBP (mmHg) | 80.99 14.88 | 85.24 14.3 | –11.934 | 0.001 | |
PP (mmHg) | 55.42 21.05 | 56.65 20.89 | –2.417 | 0.016 | |
Heart rate (beats/min) | 79.97 13.05 | 79.79 12.37 | 0.583 | 0.560 | |
Biochemical analysis | |||||
AST (U/L) | 26.53 39.35 | 27.66 18.43 | –1.389 | 0.165 | |
Uric acid (µmol/L) | 314.4 95.28 | 350.64 96.64 | –15.630 | 0.001 | |
Cholesterol (mmol/L) | 4.48 1.07 | 4.51 1.01 | –1.386 | 0.166 | |
HDL (mmol/L) | 1.16 0.32 | 1.05 0.28 | 15.445 | 0.001 | |
LDL (mmol/L) | 2.8 0.98 | 2.91 0.96 | –4.552 | 0.001 | |
FBG (mmol/L) | 5.75 1.76 | 6.05 1.83 | –6.882 | 0.001 | |
Hemoglobin (g/dL) | 131.88 18.29 | 138.37 17.84 | –14.777 | 0.001 | |
Total protein (g/dL) | 66.15 6.42 | 66.63 6.1 | –3.140 | 0.002 | |
Albumin (g/dL) | 43.31 4.75 | 43.84 4.43 | –4.686 | 0.001 | |
eGFR (mL/min/1.73 m2) | 115.71 37.82 | 116.1 36.34 | –0.429 | 0.668 | |
Arterial stiffness parameters | |||||
API | 30.31 8.11 | 31.27 7.9 | –4.911 | 0.001 | |
API 31 | 2115 (41.9) | 1252 (48.6) | 30.774 | 0.001 |
Note: Data are shown as mean SD, percent or number (%) of event outcomes. BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; PP, pulse pressure; AST, aspartate aminotransferase; HDL, high-density lipoprotein; LDL, low-density lipoprotein; FBG, fasting blood glucose; eGFR, estimated glomerular filtration rate; API, arterial pressure volume index.