Table 2. Atopic assessments and diagnoses.
| All N (%) | Females N (%) | Males N (%) | P value* | |
| Spirometry, FEV1† | ||||
| FEV1, L<80% | 35 (9.5) | 11 (5.9) | 24 (13.2) | 0.03 |
| FEV1, L<90% | 173 (46.8) | 93 (49.5) | 80 (44.0) | 0.31 |
| sRaw | ||||
| sRaw kPa/s>1.6 (%) | 28 (7.6) | 12 (6.4) | 16 (8.8) | 0.52 |
| Methacholine provocation, median PD20/µmol‡ | 225.40 | 186.2 | 298.6 | 0.01 |
| % <cut-off off | 17 (4.6) | 8 (4.3) | 9 (5.0) | |
| Feno>25 ppb§ (%) | 104 (28.1) | 40 (21.3) | 64 (35.2) | <0.01 |
| IgE total x 103 IU/L, median (IQR)§ | 80.0 (28.0–238.1) | 69.4 (25.0–216.5) | 103.9 (32.4–262.6) | 0.06 |
| Positive specific IgE any kU/L, N (%)§ | 192 (51.9) | 80 (42.6) | 112 (61.5) | <0.01 |
| Positive specific IgE food kU/L, N (%)§ | 72 (19.5) | 34 (18.1) | 38 (20.9) | 0.6 |
| Positive specific IgE inhalation kU/L, N (%)§ | 188 (50.8) | 78 (41.5) | 110 (60.4) | <0.01 |
| Positive SPT any (%) | 176 (47.6) | 75 (39.9) | 101 (55.5) | <0.01 |
| Positive SPT food (%) | 28 (7.6) | 11 (5.9) | 17 (9.3) | 0.23 |
| Positive SPT inhalation (%) | 175 (47.3) | 74 (39.4) | 101 (55.5) | <0.01 |
| Asthma, current (%) | 93 (25.1) | 46 (24.4) | 47 (25.8) | 0.86 |
| Asthma, ever (%) | 164 (44.3) | 77 (41.0) | 87 (47.8) | 0.44 |
| Rhinitis, current (%) | 143 (38.6) | 62 (33.0) | 81 (44.5) | 0.06 |
| Atopic dermatitis, current (%) | 38 (10.3) | 25 (13.3) | 13 (7.14) | 0.05 |
Bold values represent p-values at or below the significance level of 0.05.
*
Significance between the genders is calculated with t-test. In causes of not normal distributed data, Wilcoxon test has been used.
†
Calibrated for sex, height and age.
‡
PD20 is the median dose of methacholine that causes a 20% reduction in FEV1. The test is positive when a 20% reduction in FEV1 is coursed by a PD20 <8 µmol.
§
Normal range FeNO <25 ppb.
FeNOfractional exhaled nitric oxideFEV1forced expiratory volume in 1 sSPTskin prick testsRawspecific airway resistance