REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Anti-CD107a	BD Biosciences	RRID:AB_396136
Anti-CD3	BD Biosciences	RRID:AB_397038
Anti-CD16	BD Biosciences	RRID:AB_396864
Anti-CD56	BD Biosciences	RRID:AB_396853
Anti MIP-1β	BD Biosciences	RRID:AB_393549
Anti-IFNγ	BD Biosciences	RRID:AB_400425
Anti-guinea pig complement C3 goat IgG fraction, FITC	MP Biomedicals	RRID:AB_2334913
Goat anti-Mouse IgG Fc Cross-Adsorbed Secondary Antibody, PE	Thermo Fischer	RRID:AB_429715
Mouse Anti-rhesus IgG-PE (SB108a)	Southern Biotech	RRID:AB_2796071
Anti-rhesus IgG1 [7H11]	NHP Reagent Resource	RRID:AB_2819310
Anti-rhesus IgG2 [3C10]	NHP Reagent Resource	RRID:AB_2895607
Anti-rhesus IgG3 [2G11]	NHP Reagent Resource	RRID:AB_2819316
Anti-rhesus IgG4 [7A8]	NHP Reagent Resource	RRID:AB_2819322
Anti-rhesus IgA [9B9]	NHP Reagent Resource	RRID:AB_2819303
Anti-Secretory IgA	Invitrogen	RRID:AB_931432
Anti-rhesus IgM	Life Diagnostics	2C11-1-5
Biological samples
LowTox Guinea Pig Complement	CedarLane Labs	Cat # CL4051
Chemicals, peptides, and recombinant proteins
SARS-CoV-2 WT Spike	Sino Biological	40589-V08H4
SARS-CoV-2 BA1 RBD	Sino Biological	40592-V08H129
SARS-CoV-2 WT S2	Sino Biological	40590-V08B
SARS-CoV-2 WT NTD	Sino Biological	40591-V49H
SARS-CoV-2 Alpha Spike	Sino Biological	40589-V08B6
SARS-CoV-2 Beta Spike	Sino Biological	40589-V08B7
SARS-CoV-2 WT N	Sino Biological	40588-V08B
SARS-CoV-2 Delta Spike	Sino Biological	40589-V08B16
SARS-CoV-2 Gamma Spike	Sino Biological	40589-V08B10
SARS-CoV-2 XBB1.5 Spike	Sino Biological	40589-V08H45
SARS-CoV-2 BA1 Spike	Sino Biological	40589-V08H26
SARS-CoV-2 HCMV gB	Sino Biological	10202-V08H1
SARS-CoV-2 XBB1.16 Spike	Sino Biological	40589-V08H48
SARS-CoV-2 Alpha RBD	Sino Biological	40592-V08H82
SARS-CoV-2 SARS Spike	Sino Biological	40634-V08B
SARS-CoV-2 Beta RBD	Sino Biological	40592-V08H59
SARS-CoV-2 EG5 Spike	Sino Biological	40589-V08H55
SARS-CoV-2 BA2.86 Spike	Sino Biological	40589-V08H58
SARS-CoV-2 EG5 RBD	Sino Biological	40592-V08H151
SARS-CoV-2 Delta RBD	Sino Biological	40592-V08H91
SARS-CoV-2 Ebola Glycoprotein	Sino Biological	40459-V08H
SARS-CoV-2 Gamma RBD	Sino Biological	40592-V08H86
SARS-CoV-2 BA2 Spike	Sino Biological	40589-V08H28
SARS-CoV-2 BA2 RBD	Sino Biological	40592-V08H123
SARS-CoV-2 BA5 Spike	Sino Biological	40589-V08H32
SARS-CoV-2 BA5 RBD	Sino Biological	40592-V08H131
SARS-CoV-2 BQ1.1 Spike	Sino Biological	40589-V08H41
SARS-CoV-2 BQ1.1 RBD	Sino Biological	40592-V08H143
SARS-CoV-2 XBB1.5 RBD	Sino Biological	40592-V08H146
SARS-CoV-2 XBB1.16 RBD	Sino Biological	40592-V08H136
Rhesus soluble Fcγ2A-1	Duke University	Custom Order
Rhesus soluble Fcγ2A-2	Duke University	Custom Order
Rhesus soluble Fcy2A-3	Duke University	Custom Order
Rhesus soluble Fcy2A-4	Duke University	Custom Order
Rhesus soluble Fcγ3A-1	Duke University	Custom Order
LC-LC-Sulfo-NHS Biotin	ThermoFisher	Cat # A35358
Brefeldin A	Sigma Aldrich	Cat #B7651
GolgiStop	BD Biosciences	Cat # 554724
Streptavidin-R-Phycoerythrin	Prozyme	Cat # PJ31S
Critical commercial assays
Fix & Perm Cell Permeabilization Kit (Medium B)	ThermoFisher	GAS002S100
Fix & Perm Cell Permeabilization Kit (Medium A)	ThermoFisher	GAS001S100
EasySep™ Direct Human Neutrophil Isolation Kit	Stemcell Technologies	19666
EasySep™ Human NK Cell Isolation Kit	Stemcell Technologies	17955
NHS-Sulfo-LC-LC Kit	ThermoFisher	21435
Zebra-Spin Desalting and Chromatography Columns	ThermoFisher	89882
Experimental models: Cell lines
THP-1 monocytes	ATCC	RRID: CVCL_0006
Human Primary Natural Killer Cell Leukopack	StemCell	200–0092
Software and algorithms
GraphPad Prism 8	GraphPad Software, Inc.	RRID:SCR_002798
iQue Forecyt 9.1	Sartorius	60028
R Studio V 6.0	R Project for Statistical Computing	RRID:SCR_000432
Flow Jo	BD Bioscience	RRID:SCR_008520
MATLAB ver. R2019a	MathWorks	RRID:SCR_001622
Other
384-well HydroSpeed Plate Washer	Tecan	30190112
iQue Screener Plus	Intellicyt/Sartorius	11811
MagPlex Microspheres	Luminex MFG	MC12001-01 (Cataloged by region)
Green Fluorescent Neutravidin Microspheres	ThermoFisher	Custom Synthesis
Red Fluorescent Neutravidin Microspheres	ThermoFisher	Custom Synthesis
Scarlet Fluorescent Neutravidin Microspheres	ThermoFisher	Custom Synthesis
384-well HydroSpeed Plate Washer	Tecan	30190112
MagPlex Microspheres	Luminex MFG	MC12001-01 (Cataloged by region)
Green Fluorescent Neutravidin Microspheres	ThermoFisher	Custom Synthesis
Red Fluorescent Neutravidin Microspheres	ThermoFisher	Custom Synthesis
Scarlet Fluorescent Neutravidin Microspheres	ThermoFisher	Custom Synthesis
Systems Serology Dataset	GitHub	BDRPM_20240422
Existing dataset including neutralizing antibody titers and viral loads	McMahan et al.28