Endothelial c-Myc knockout promotes systemic inflammation. (A) Monocyte, neutrophil, and lymphocyte fraction of total white blood cells analyzed from CT and EC-Myc KO complete blood count (n = 6). (B) Multiplex analysis of selected inflammatory mediators in serum significantly altered by endothelial c-Myc knockout (n = 11). CT, control; EC-Myc KO, endothelial c-Myc knockout. *p < .05, **p < .01