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. Author manuscript; available in PMC: 2024 Sep 2.
Published in final edited form as: FASEB J. 2022 Jan;36(1):e22077. doi: 10.1096/fj.202101086R

FIGURE 2.

FIGURE 2

Differential gene expression of CT and EC-Myc KO mice after short-term exposure to HFD. (A) Volcano plots indicating the number of genes significantly altered in EC-Myc KO mice relative to CT under CTD. (B) Volcano plots indicating the number of genes significantly altered by HFD exposure in CT and EC-Myc KO livers. (C) Venn diagrams indicating the number of genes significantly altered by HFD exposure in CT and EC-Myc KO livers. The top panels represent results in males (n = 4) and the bottom panels represent results in females (n = 3). CT, control; CTD, low-fat control diet; EC-Myc KO, endothelial c-Myc knockout; HFD, high-fat diet