Analysis of HCC-related genes in EC-Myc KO liver after short-exposure to HFD. Venn diagrams indicating the number of inflammation, fibrosis, and HCC-related genes in male (left panel) and female (right panel) mice significantly altered by HFD exclusively in EC-Myc KO livers (n = 3–4). Genes marked in blue are present in both male and female animals. EC-Myc KO, endothelial c-Myc knockout; HCC, hepatocellular carcinoma; HFD, high-fat diet