Scores of pyrrolone (15A) with 229E, IBV, MERS, and SARS viruses^a.

Structure	Virus	S	rmsd_refine	E_conf	E_place	E_score1	E_refine	E_score2
	229E	−25.75	3.95	158.57	−69.03	−20.80	−23.16	−25.75
	IBV	−19.65	2.56	157.27	−85.14	−26.71	−24.76	−19.65
	MERS	−20.16	1.62	178.04	−77.59	−10.42	40.05	−20.99
	SARS	−20.84	1.67	198.40	−3.40	−25.18	227.71	−20.13

^a S (Score): the overall docking score (lower values indicate better binding). All energy values are in kcal mol⁻¹. rmsd_refine: root mean square deviation after refinement E_conf: conformer energy. E_place: placement energy E_score1: initial scoring function energy. E_refine: refinement energy E_score2: final scoring function energy.