Table 1.
Baseline characteristics of the study population
| Clinical features | |
| Age (years) | 46.4 ± 12.5 |
| Women | 412 (84) |
| Heart rate (bpm) | 70.6 ± 13.9 |
| Systolic blood pressure (mmHg) | 116 ± 16 |
| Diastolic blood pressure (mmHg) | 75 ± 11 |
| NYHA functional Class III/IV | 185 (37.2) |
| Previous embolic events | 102 (20.7) |
| Previous valvuloplastya | 159 (32.2) |
| Anticoagulation therapy | 204 (41.4) |
| Sinus rhythm | 327 (66.3) |
| Atrial fibrillation | 166 (33.7) |
| Echocardiographic data | |
| LV end-diastolic diameter (mm) | 48.4 ± 6.4 |
| LV end-systolic diameter (mm) | 31.8 ± 5.7 |
| LV ejection fraction (%) | 62 ± 7.9 |
| LA volume (mL/m2) | 62 ± 27 |
| Mitral valve area (cm2) | 1.11 ± 0.4 |
| Mean gradient (mmHg) | 10.2 ± 4.9 |
| SPAP (mmHg) | 44.7 ± 18.1 |
| RV-FAC (%) | 46.1 ± 10.3 |
| TR moderate/severe | 82 (16.6) |
| Net atrioventricular compliance (Cn) (mL/mmHg) | 5.1 ± 1.9 |
| LA strain | |
| LASr (%) | 12.5 ± 7.1 |
| LAScd (%) | 6.7 ± 4.1 |
| LASct (%) | 6.0 ± 4.2 |
Data are expressed as absolute numbers (percentage) or the mean value ± standard deviation.
FAC, right ventricular fractional area change; LA, left atrial; LAScd, left atrial strain during the conduit phase; LASct, Left atrial strain during the contractile phase; LASr, left atrial strain during the reservoir phase; LV, left ventricular; NYHA, New York Heart Association; SPAP, systolic pulmonary artery pressure; TR, tricuspid regurgitation.
aSurgical commissurotomy or percutaneous valvuloplasty in the past [85 patients (16.9%) percutaneous valvuloplasty, 58 patients (11.5%) surgical commissurotomy; 16 patients (3.2%) both surgical and percutaneous valvuloplasty].