Table 3.

Significantly enriched GO terms related to cardiovascular system and response to hypoxia for adaptive introgressed genes in the TZG population

Term ID	Term description	P value	Genes
GO:0060982	Coronary artery morphogenesis	< 0.001	Nrp1 (neuropilin 1), Arid2 (AT-rich interaction domain 2)
GO:0010613	Positive regulation of cardiac muscle hypertrophy	< 0.001	Ankrd55 (ankyrin repeat domain 55), Ece1 (endothelin-converting enzyme 1)
GO:0048008	Platelet-derived growth factor receptor signaling pathway	0.01	Fer (FER tyrosine kinase), Nrp1
GO:0008217	Regulation of blood pressure	0.02	Corin (corin, serine peptidase), Ece1
GO:1,904,753	Negative regulation of vascular associated smooth muscle cell migration	0.03	Prkg1 (protein kinase cGMP-dependent 1)
GO:0005021	Vascular endothelial growth factor-activated receptor activity	0.03	Nrp1
GO:0035912	Dorsal aorta morphogenesis	0.03	Rbpj (recombination signal binding protein for immunoglobulin kappa J region)
GO:0097746	Regulation of blood vessel diameter	0.03	Ece1
GO:0060087	Relaxation of vascular smooth muscle	0.04	Prkg1
GO:0045822	Negative regulation of heart contraction	0.04	Prkg1
GO:0003198	Epithelial to mesenchymal transition involved in endocardial cushion formation	0.05	Rbpj
GO:0003214	Cardiac left ventricle morphogenesis	0.05	Rbpj
GO:0001666	Response to hypoxia	0.05	Nox4 (NADPH oxidase 4), Ece1, Pam (peptidylglycine alpha-amidating monooxygenase)

P ≤ 0.05 was considered statistically significant