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. 2024 Aug 29;17:3227–3238. doi: 10.2147/DMSO.S462748

Table 2.

Analysis of Variations in Blood Pressure, Blood Lipids, and Other Parameters Based on HbA1c Classification

Variables HbA1c, %
<6.3 6.3–7.2 7.2–8.6 >8.6 P value
Age, y 55.77 ± 10.08 59.0 ± 9.25 58.21 ± 9.64 55.86 ± 9.96 <0.001
Sex, n 0.085
 Male 202 (44.8) 203 (48.1) 220 (52.0) 219 (52.3)
 Female 249 (55.2) 219 (51.9) 203 (48%) 200 (47.7)
BMI, kg/m² 25.83 ± 3.85 26.04 ± 3.46 26.35 ± 3.45 26.06 ± 3.77 0.198
WC, cm 88.02 ± 9.67 89.67 ± 9.67 91.09 ± 9.58 90.57 ± 9.87 <0.001
Waist groups, n 234 (51.9) 255 (60.4) 269 (63.6) 253 (60.4) 0.003
Years of diabetes, n 5.94 ± 4.46 8.01 ± 5.75 8.92 ± 6.19 9.66 ± 5.56 <0.001
Hypertension, n 245 (54.3) 231 (54.7) 208 (49.2) 175 (41.8) <0.001
Dyslipidemia, n 278 (61.6) 275 (65.2) 287 (67.8) 282 (67.3) 0.202
Current smoking, n 84 (18.6) 59 (14.0) 96 (22.7) 98 (23.4) 0.002
Current alcohol drinking, n 128 (28.4) 102 (24.2) 130 (30.7) 120 (28.6) 0.191
Physical activity 299 (66.3) 276 (65.4) 273 (64.5) 280 (66.8) 0.903
Laboratory results, mmol/L
 TC 5.13 ± 1.17 5.00 ± 1.08 5.11 ± 1.09 5.47 ± 1.35 <0.001
 TG 2.17 ± 2.77 2.00 ± 1.54 2.28 ± 2.01 2.90 ± 3.70 <0.001
 LDL-C 3.02 ± 0.94 2.99 ± 0.95 3.05 ± 0.93 3.20 ± 1.04 0.009
 HDL-C 1.49 ± 0.42 1.42 ± 0.38 1.40 ± 0.40 1.41 ± 0.46 0.012
Family history, n
 Family history of diabetes 173 (38.4) 191 (45.3) 193 (45.6) 210 (50.1) 0.006
 Family history of obesity 135 (29.9) 131 (31.0) 137 (32.4) 150 (35.8) 0.283
 Family history of coronary heart disease 101 (22.4) 89 (21.1) 78 (18.4) 79 (18.9) 0.418
 Family history of stroke 112 (24.8) 103 (24.4) 96 (22.7) 82 (19.6) 0.247
 Family history of malignant tumor 92 (20.4) 87 (20.6) 80 (18.9) 99 (23.6) 0.394
 Family history of hyperlipidemia 109 (24.2) 100 (23.7) 85 (20.1) 109 (26.0) 0.229
 Family history of hypertension 282 (62.5) 259 (61.4) 263 (62.2) 257 (61.3) 0.979
Insulin/oral medicine/no medication taken, n 0.135
 Insulin 54 (12.0) 47 (11.1) 40 (9.5) 60 (14.3)
 Oral medicine 342 (75.8) 306 (72.5) 316 (74.7) 309 (73.7)
 No medication taken 55 (12.2) 69 (16.4) 67 (15.8) 50 (11.9)
Antihypertensive drugs, n 207 (45.9) 200 (47.4) 181 (42.8) 152 (36.3) 0.006
Lipid-lowering drugs, n 63 (14.0) 67 (15.9) 71 (16.8) 44 (10.5) 0.047

Notes: Data are presented as means ± standard deviation, or numbers (percentage (%)). HbA1c indicates glycosylated haemoglobin.

Abbreviations: BMI, body mass index; WC, waist circumference; TC, total cholesterol; TG, triglycerides; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol.