Fig. 1.
Response to belzutifan in a patient with VHL-associated bilateral RHs. Right eye (a) and left eye (b) show color fundus photographs and optical coherence tomography (OCT) of a patient with bilateral optic disc angiomas with associated cystoid macular edema that had been treated with a combination of PDT laser, focal laser, intravitreal anti-VEGF, and intravitreal and subtenon’s steroids to both eyes and external beam radiation to the right eye. Right eye (c) and left eye (d) show color fundus photographs and OCT images of the patient after 9 months of treatment with systemic belzutifan with regression of the tumors and marked improvement in the cystoid macular edema on OCT.
