Fig. 2.

Wide-field color fundus photographs of an eye with choroidal melanoma before treatment with plaque brachytherapy with PPV, trans-vitreal biopsy, silicone oil insertion, endolaser, cryotherapy, and prior to ocular tumor lysis (a) and 15.5 months later when ocular tumor lysis occurred (b). Prior to plaque brachytherapy and tumor lysis, the tumor exhibited a collar-button configuration and adjacent inferior subretinal fluid. Ocular tumor lysis presented with extensive subretinal and preretinal pigment dispersion, tumor necrosis with overlying retinal necrosis, and a total exudative retinal detachment.