Table 2.
Clinical details, ease of surgery score, and response to neoadjuvant systemic chemotherapy in 10 patients of SGC
| S. No. | Age/sex | Lat./eyelid | Primary/recurrent | Previous surgery | AJCC | % reduction/RECIST | Surgery planned | EOS score/category | TRT outcome and follow-up, months | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| before after NACT | before after NACT | |||||||||||
| before after NACT | ||||||||||||
| 1 | 40/F | RU | Recurrent | Tenzel’s flap | T2CN0M0 | T1c N0M0 | 75/PR | Lid-sharing procedure | Direct closure | 10/7 | 2/1 | Alive (77) |
| 2 | 44/M | RU | Primary | – | T3b N0M0 | T2b N0M0 | 54.16/PR | Lid-sharing procedure | Hugh’s procedure | 13/9 | 3/2 | Alive (33) |
| 3 | 42/M | LU | Recurrent | Excision with direct closure | T3c N0M0 | T3c N0M0 | 88.7*/PR | Lid-sharing procedure | Cutler beard^ | 16/12 | 3/3 | Alive (35) |
| 4 | 70/M | LL | Primary | – | T4b N1M0 | T4b N0M0 | 11.76/SD | Exenteration | Exenteration | 17/16 | 3/3 | ##Died of disease (27) |
| 5 | 65/M | RU | Primary | – | T4a N0M0 | T3c N0M0 | 53.12/PR | Exenteration | Cutler beard | 17/12 | 3/3 | Lost to follow-up (26) |
| 6 | 49/M | RL | Recurrent | Tenzel’s flap | T3c N0M0 | T1c N0M0 | CR | Lid-sharing procedure | Hugh’s procedure | 17/12 | 3/3 | Alive (32) |
| 7 | 55/F | RL | Recurrent | Tenzel’s flap | T4a N0M0 | T4a N0M0 | >60* PR | Exenteration | Exenteration | 20/20 | 3/3 | Alive (31) |
| 8 | 45/F | RU | Primary | – | T4a N0M0 | T4a N0M0 | >90%*/PR | Exenteration | Reverse cutler beard | 17/11 | 3/2 | Alive (23) |
| 9 | 60/F | L | Primary | – | T3c N0M0 | T2c N0M0 | 36.84/PR@ | Lid-sharing procedure | Direct closure | 12/9 | 3/2 | Died of unrelated cause (22) |
| 10 | 57/F | RU | Recurrent | Orbitotomy with tumour debulking | T4a N0M0 | T4a N0M0 | >90%*, PR# | Exenteration | Exenteration | 17/17 | 3/3 | Alive (23) |
*On imaging.
**All lid tissue that appeared to have post-tumour regression changes was removed.
$Orbital tumour disappeared completely, eyelid thickening reduced but persisted.
#Thickening of the upper eyelid persisted.
@Lid lengthening due to weight of the tumour allowed direct closure despite partial regression,
#Exenteration done in view of pathological confirmation of residual orbital tumour.
^More than 75% of length involved despite PR.
##Denied radicle LN dissection and EBRT.