Figure 1. Time-course analysis of the transcriptome of Synechocystis on entry to the microoxic conditions.
(A) Schematic diagram for the sampling of cells under aerobic and microoxic conditions. (B) Gene set enrichment analysis on time-course transcriptome data. KEGG pathways enriched in upregulated or downregulated genes after 1, 2, and 4 hr incubation under microoxic conditions are shown. (C) (Left) Heatmap showing expression change in all upregulated genes over the time course. Genes classified into transient (striped square), plateau (open square), continuous (filled square), and late (dotty square) were clustered into subgroups and sorted by the gene name. (Right) Examples of genes are classified into each expression pattern. (D) The classified genes were mapped to central carbon metabolism, centered on pyruvate. PEP: phosphoenolpyruvate, PYR: pyruvate, AcCoA: acetyl CoA, Ac-P: acetyl phosphate, OXA: oxaloacetate, PHB: polyhydroxy butyrate, TCA: tricarboxylic acid cycle.
Figure 1—figure supplement 1. Schematic diagram showing the classification of genes according to the time-course transcriptome.
