. 2024 May 28;8(5):826–835. doi: 10.1002/ags3.12829

TABLE 1.

Clinicopathological variables and preoperative IBI in CRC patients.

Variables	N	Preoperative IBI	p value
Variables	N	Median (IQR)	p value
Sex
Male	327	0.37 (0.12–1.37)	0.03 ^a ,^*
Female	228	0.26 (0.08–1.53)
Median age (y)
>68	276	0.36 (0.11–1.33)	0.49 ^a
≤68	279	0.29 (0.1–1.53)
Neoadjuvant therapy
Yes	68	0.39 (0.12–2.21)	0.33 ^a
No	487	0.33 (0.1–1.39)
Obstruction/perforation/abscess
Present	41	6.84 (0.57–22.0)	<0.0001 ^a ,^*
Absent	514	0.29 (0.09–1.23)
Histological type
Differentiated	502	0.3 (0.1–1.23)	<0.0001 ^a ,^*
Undifferentiated	53	1.33 (0.33–20.1)
Location
Colon	339	0.4 (0.1–2.16)	0.02 ^a ,^*
Rectum	216	0.27 (0.09–1.04)
Pathological T category
pT1/T2	189	0.15 (0.06–0.39)	<0.0001 ^a ,^*
pT3/T4	366	0.56 (0.17–3.72)
Venous invasion
Present	269	0.42 (0.12–2.98)	0.002 ^a ,^*
Absent	286	0.25 (0.08–1.02)
Lymphatic invasion
Present	367	0.44 (0.12–2.75)	<0.0001 ^a ,^*
Absent	188	0.22 (0.08–0.77)
Lymph node metastasis
Present	225	0.58 (0.16–3.77)	<0.0001 ^a ,^*
Absent	330	0.25 (0.08–0.89)
Distant metastasis
Present	102	1.92 (0.44–9.37)	<0.0001 ^a ,^*
Absent	453	0.25 (0.08–0.9)
UICC stage classification
Stage I	157	0.13 (0.06–0.36)	<0.0001 ^b ,^*
Stage II	149	0.37 (0.14–1.76)
Stage III	147	0.34 (0.12–1.08)
Stage IV	102	1.92 (0.44–9.37)

Abbreviations: CRC, colorectal cancer; IBI, Inflammatory Burden Index; IQR, interquartile range.

^{^a}

Mann–Whitney test.

^{^b}

Kruskal–Wallis test.

p < 0.05.